1. Acute toxicity
Rat oral LD50: 650mg/kg.
2. Irritation
Rabbit via eye: 100 μ 50. Severe irritation.
3. Mutagenicity
Microbial mutagenicity: Salmonella typhimurium 10 μ G/dish. DNA inhibition: 200mg/kg by mouth in mice;
4. Carcinogenicity
IARC carcinogenicity review: G3, insufficient evidence of carcinogenicity to humans and animals.
5. Other
The lowest toxic dose of TDLo in the abdominal cavity of rats was 375mg/kg (30 days, male), which caused fetal death.